Heart Valves Dual Chamber Pulse Duplicator
Dual Chamber Pulse Duplicator

 

 

 

 

 

 

 

 

Heart Valve Testing – Pulsatile Flow: Measured parameters

  • Valve pressure gradient
  • Geometric Orifice Area (valve opened)
  • Regurgitation Orifice Area (valve closed)
  • Effective Orifice Area (EOA)
  • Measure regurgitant volumes for different operating conditions
  • Assess kinematics of valve leaflets

Heart Valve Testing - Pulsatile Flow: Scope

  • Hydrodynamic performance of artificial heart valves prosthesis
  • Hydrodynamic performance of any valvular prosthesis
  • Hydrodynamic performance of surgical, transapical, TAVI and any transcatheter valve
  • Hydrodynamic performance of biological, polyester, mechanical valves

 

 

Heart Valve Testing - Pulsatile Flow: Associated tests

  • Flow characterization studies (PIV & Echo Doppler)
  • Device pre-conditioning - Simulated use on IDTE 2000
  • Accelerated Stent Fatigue Testing
  • Post deflection, Burst pressure, Valve migration
  • Accelerated Wear and Tear
  • Corrosion resistance
  • Steady Flow Testing
  • Leaflet kinematics
  • Ring integrity, Ring push off, Ring torque
  • Stent creep (polymeric stent)
  • Leaflet impingement & escape force (mechanical valve)

 

ProtomedLabs uses a proprietary and validated dual chamber pulse duplicator for hydrodynamic performance testing of heart valves. The pressure difference and the regurgitant volume are evaluated in-vitro under different flow conditions. Left ventricular stroke volume, heart rate and diastolic and systolic aortic pressures can easily be modified to customer’s requirements. The repeatability of measurements is ensured by a servo-control, which also monitors pressure and flow waveforms. The valve samples are compared to reference valves used clinically.

TEST METHODE

TEST DESCRIPTION

PERFORMANCE PARAMETERS

Pulsatile-flow testing Measurements of the trans-valvular pressure difference and valve effective orifice area at various simulated cardiac outputs and simulated normal heart rates
  1. Measure valve pressure gradient under physiological pulsatile conditions
  2. Geometric Orifice Area (valve opened)
  3. Regurgitation Orifice Area (valve closed)
  4. Evaluate the Effective Orifice Area (EOA) of the valve
  5. Assess kinematics of valve leaflets
Measurements of the regurgitant volumes and fraction at different mean back pressures, at simulated heart rates and normal cardiac output.
  1. Measure regurgitant volumes for different operating conditions
  2. Evaluate the Effective Orifice Area (EOA) of the valve
  3. Assess kinematics of valve leaflets